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Atletico Madrid were held to a 1-1 draw at Alaves as Lucas Perez's sublime solo strike stopped the visitors from picking up three points.
Sevilla climbed to the top of La Liga on Sunday after beating Alaves 1-0 away from home.
Valencia took control of the battle for the final Champions League qualifying place in La Liga by beating Alaves 3-1 to climb above Getafe.
Barcelona inched closer to their 26th La Liga title with a 2-0 victory at Alaves on Tuesday.
Sevilla improved their chances of qualifying for the Champions League by beating fellow top-four chasers Alaves 2-0 at home on Thursday.
Atletico Madrid thrashed Alaves 4-0 on Saturday to keep alive their faint hopes of winning the La Liga title as they stayed 10 points behind leaders
Karim Benzema scored his sixth goal in four games as Real Madrid beat Alaves 3-0 on Sunday for a fourth successive La Liga victory.
Borja Baston earned high-flying Alaves a 1-1 draw at Girona on Saturday in La Liga after Cristhian Stuani's brilliant bicycle kick sent the hosts ah
Atletico Madrid moved into provisional second place in La Liga with a 3-0 win over fourth-placed Alaves on Saturday to join leaders Barcelona on 28
Sevilla slipped off the top of La Liga on Sunday as they could only draw 1-1 at Alaves, whose comfortable protection of their unbeaten home record a
Alaves spurned the chance to go top of La Liga on Friday with a 1-0 defeat at Leganes, who moved out of the relegation zone.
Real Madrid's miserable run of results continued as they slid to a shock 1-0 La Liga defeat at Alaves and failed to score in a fourth-straight game.
Barcelona began the new La Liga campaign with a 3-0 win over Alaves on Saturday with the help of a spectacular under-the-wall free kick from Messi.
The Ghana international signed a four-year deal with the Spanish side on Monday.
Morocco's football federation has lost its case against FIFA to recruit Spain forward Munir El Haddadi before the World Cup.
Atletico Madrid stayed mathematically in the La Liga title race, for a few hours at least, with a 1-0 victory over Alaves.
Alvaro Medran, on loan from Valencia, showed his frustration over his lack of playing time at Alaves by crying during a postgame interview.
Morocco's hopes of adding Munir El Haddadi to their World Cup squad have been dashed by FIFA.
Simone Zaza scored one goal and set up another for Rodrigo Moreno as Valencia claimed a 3-1 La Liga win over Alaves at the Mestalla Stadium.
Cristiano Ronaldo scored twice to lead Real Madrid to a 4-0 rout of Alaves at the Bernabeu on Saturday.