Real Sociedad are on track to reach the Copa del Rey final for the first time in 32 years after beating second division Mirandes.
Athletic Bilbao dominated Granada in the Copa del Rey semifinal first leg but were only able to earn a 1-0 win on Wednesday.
Real Madrid came back from a goal down to beat Osasuna 4-1 in La Liga on Sunday with the help of captain Sergio Ramos.
Barca continue to feel victimised by referees after another big decision went against them in Copa del Rey exit at the hands of Athletic Bilbao.
For the first time in 17 years, neither Real Madrid nor Barcelona are in the Copa del Rey semifinals. Here's how a stunning night in Spain unfolded.
Real Madrid's players were appalled at their defensive display in their 4-3 Copa del Rey defeat to Real Sociedad.
"Abidal was a player ... and that's why he should know what it's like inside the dressing room and how players feel," Alba said.
Real Madrid and Barcelona's Copa del Rey losses were the first time in nearly 65 years that they were ousted from the tournament on the same day.
Barcelona were bounced from the Copa del Rey, as they failed to take advantage of their attacking superiority and were punished by Athletic Bilbao.
Barcelona were sent out of the Copa del Rey as they were beaten 1-0 at Athletic Bilbao after a stoppage time header from Inaki Williams.
Real Madrid's saw their 21-game unbeaten run snapped as they were bounced from the Copa del Rey by Alexander Isak, Martin Odegaard & Real Sociedad.
Real Madrid had their 21-match unbeaten streak snapped with 4-3 defeat to visitors Real Sociedad to crash out of the Copa del Rey.
Quique Setien said he has no regrets about accepting the coaching job at Barcelona after the club descended into crisis on Tuesday.
Roberto Soldado scored a stoppage time penalty to send Granada into the Copa del Rey semi-finals with a 2-1 win over holders Valencia on Tuesday.
Barcelona have been handed a daunting trip to Athletic Bilbao in the quarterfinals of the Copa del Rey, while Real Madrid play Real Sociedad.
Lionel Messi was directly involved in all five of Barcelona's goals in their win over Leganes that takes them into the Copa del Rey quarterfinals.
Barcelona beat Leganes 5-0 on Wednesday to reach the Copa del Rey quarterfinals as Lionel Messi scored twice in the easy win.