Mikko Rantanen left the Avalanche's 3-1 loss to the St. Louis Blues on Monday in the second period due to a lower-body injury and did not return.
The All-Star right winger was skating up ice near the boards when his skate appeared to get caught in the ice, causing his left foot to go sideways.
After gathering himself, Rantanen immediately went toward the Avalanche bench and to Colorado's locker room. He was ruled out of the game late in the second period.
The team had no update on Rantanen's condition after the game.
"I have no idea [if the injury is serious]. I mean, he wasn't good enough to continue tonight as far as I know," Colorado coach Jared Bednar said. "We'll just have to re-evaluate him in the morning and see what happens."
Rantanen leads the team with five goals and 11 points this season.