Al Horford added 20 points, nine rebounds and eight assists. Jayson Tatum chipped in 17 points to help Boston improve to an NBA-best 21-4. The Celtics have won five of their last six.
"We're just utilizing our strength's -- me realizing that he can use me and I can use him," Irving said. "When we utilize each other, we can get other guys great shots."
The Celtics shot 50 percent or better from the field for the fifth straight game. That's their longest such streak since 2010.
"I think it's just the work I've been putting in. It's starting to pay off for me," Horford said. "I feel like we're starting to find our rhythm as a group, and I'm finding my rhythm, too."
"You have to compete against them because they don't stop playing hard," Antetokounmpo said. "From start to finish they play hard and play together."
Boston led by as many as 20 in the third quarter, before the Bucks stormed back, thanks in large part to Antetokounmpo. He almost singlehandedly kept the Bucks in it, scoring 16 points in the period and trimming Boston's lead to 88-81 entering the fourth.
It was 104-97 following a free-throw by Bledsoe, but the Celtics got five straight points from Irving to get the lead back up to 12 with less than a minute to play.
Antetokounmpo and Middleton entered Monday as the most productive scoring duo in the Eastern Conference, averaging a combined 49 points per game.
They combined for 59 Wednesday. It offset some early inconsistency from the rest of their teammates, which went just 6 of 24 from the field in the first half.
Bucks: Bench was outscored 18-4 in the first half.
Celtics: Are now 11-2 at TD Garden this season, the most home victories in the NBA. ... Outscored Milwaukee 60-34 in the paint. ... Tatum went 4 for 4 from the 3-point line in the first quarter. Boston shot 61 percent (11 of 18) from the field overall in the period.
"I think his mannerisms are just one that you can't see if he's rattled or not. His composure is at a very high level to only be 19." -- Milwaukee coach Jason Kidd on Tatum.
Kidd was called for technical after jawing with an official at 4:44 in second quarter. It ignited an 8-0 Celtics run that pushed Boston's lead to 56-37. Irving had five points during the run.
Irving said he could shed his protective facemask for Saturday's matchup with Utah. He has been wearing the mask since breaking a bone in his face on Nov. 10 against Charlotte.
The Celtics improved to 16-2 when scoring 100 or more points.
The Bucks haven't been held under 100 points since a 99-88 loss to Washington on Nov. 20 -- a span of six games.
Bucks: Begin a three-game homestand Wednesday against Detroit.
Celtics: Conclude five-game homestand Wednesday against Dallas.
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