Ford scored seven points and Fitts added four in a 13-2 opening run and Saint Mary's never trailed. Isaiah Wright's layup with 12:29 to play pulled San Diego within eight but the Gaels scored 14 of the next 18 points and led by at least 13 the rest of the way.
Isaiah Pineiro had 19 points and eight rebounds while Wright scored 15 for the Toreros (13-7, 2-3).
Saint Mary's used a 12-4 advantage on the offensive glass to outscore San Diego 17-2 in second-chance points.
Morant: 'I still have a lot of more work to do'
Ja Morant talks with Marty Smith about his journey to Murray State and his rise to being recognized as one of the best players in college basketball.
Iowa's struggles could continue in tourney
ESPN bracketologist Joe Lunardi says No. 10 seed Iowa peaked too early and could be in for a big loss to No. 7 seed Cincinnati.
Don't sleep on Florida State as a Final Four contender
ESPN bracketologist Joe Lunardi won't be picking Florida State in his Final Four, but he says the Seminoles are capable of reaching Minneapolis.